Memories build up the person that we are, changing day by day our brain to integrate the new information to the plastic network of knowledges formed by past experiences. It is impossible to imagine us without our memories. How are memories integrated in the neural network? How are they kept for a lifetime in our brain?
The main interest of our laboratory is to answer these questions and reveal the neural basis of the process that transform an everyday experience in a long-lasting memory. Particularly we study how memories are encoded and represented in the brain at different levels, from changes at the synaptic to the more complex network level. The Vetere Lab is part of the Brain Plasticity Laboratory at ESPCI. Visit the website page here |
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RESEARCH
ARTIFICIAL MEMORIES
Events are encoded in our brain throughout the activity of specific patterns of neuronal ensembles. We demonstrated that it is possible to reverse engineer a memory, by activating specific codes in the brain, to mimic the real experience. Our interest is to modulate patterns of activity, generated by distinct external representations, to investigate how the brain encodes external information. HOW WE STUDY IT: optogenetics, circuits, miniscope, behaviour Related paper: NN |
LONG-LASTING MEMORIES
Experiences we face every day continuously reshape our brain and, at the same time, the state of our brain can change the way we perceive the world outside us. In particular we study the plastic changes occurring in the neuronal network when we experience a new event and the changes required to form a memory of it. HOW WE STUDY IT: network, morphology, optogenetics, chemogenetics, miniscope, behaviour Related papers: Neuron, PNAS, JN |